ncRNA name | hsa-miR-24 |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB cell line Y79; RPE cell line ARPE-19 |
Methods | qRT-PCR, transfection, CCK-8 assay, transwell assay, luciferase reporter assay, Western blot |
Expression pattern | down-regulated |
Functional description | ANRIL negatively regulated the expression of miR-24, which played tumor suppressive roles in retinoblastoma cells. ANRIL positively regulated the expression of c-Myc, which was a target gene of miR-24 in retinoblastoma cells. |
PubMed ID | 30703428 |
Year | 2019 |
Title | ANRIL acts as onco-lncRNA by regulation of microRNA-24/c-Myc, MEK/ERK and Wnt/β-catenin pathway in retinoblastoma. |
Drug-related ncRNA | NO |
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