logo

        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-24
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB cell line Y79; RPE cell line ARPE-19
Methods qRT-PCR, transfection, CCK-8 assay, transwell assay, luciferase reporter assay, Western blot
Expression pattern down-regulated
Functional description ANRIL negatively regulated the expression of miR-24, which played tumor suppressive roles in retinoblastoma cells. ANRIL positively regulated the expression of c-Myc, which was a target gene of miR-24 in retinoblastoma cells.
PubMed ID 30703428
Year 2019
Title ANRIL acts as onco-lncRNA by regulation of microRNA-24/c-Myc, MEK/ERK and Wnt/β-catenin pathway in retinoblastoma.
Drug-related ncRNA NO

Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.